GAP43 anticorps (C-Term)

N° du produit ABIN5540032

Cet anticorps anti-GAP43 est un anticorps Poulet Polyclonal détectant GAP43 dans WB, IF et ICC. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour GAP43 anticorps (C-Term) (ABIN5540032)

Antigène: GAP43 (Growth Associated Protein 43 (GAP43))

Reactivité: Humain, Rat, Souris

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp GAP43 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-GAP43 anticorps

Épitope: C-Term

Specificité: This antibody detects GAP43.

Purification: Ig Fraction

Immunogène: Synthetic peptide corresponding to amino acid residues from the C-terminal region of the rat GAP43 sequence

Information d'application

Indications d'application: Western blot: 1/2000. Immunoflourescence: 1/500.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 10 mM Sodium azide

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur GAP43

Antigène: GAP43 (Growth Associated Protein 43 (GAP43))

Autre désignation: gap43

Sujet: GAP-43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration (Benowitz and Routtenberg, 1997). There is also evidence from knockout animals that GAP-43 serves to amplify pathfinding signals from the growth cone (Strittmatter et al., 1995). GAP-43 is thought to mediate at least some of these effects via interaction with actin. Importantly, phosphorylation at Ser 41 by protein kinase C modulates the interaction of GAP-43 with actin (He et al., 1997) and may also affect neurotransmitter release during forms of plasticity like LTP (Hulo et al., 2002).

UniProt: P07936